Disease: Metastatic melanoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZHX2 Q9Y6X8 zinc fingers and homeoboxes 2 Transcription factor 3.4E-02 0.510 0.654
VTN P04004 vitronectin 1.5E-10 0.509 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TFPI2 P48307 tissue factor pathway inhibitor 2 Enzyme modulator 8.4E-04 0.521 0.769
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
SPZ1 Q9BXG8 spermatogenic leucine zipper 1 0.507 0.769
SP1 P08047 Sp1 transcription factor Nucleic acid binding 1.00 0.493 0.769
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
RTL1 A6NKG5 retrotransposon Gag like 1 5.6E-03 0.554 0.808
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731
RIPK3 Q9Y572 receptor interacting serine/threonine kinase 3 Kinase 1.2E-14 0.497 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615
PTK2 Q05397 protein tyrosine kinase 2 Kinase 1.00 0.497 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923